产品货号:
Z18382
中文名称:
Integrin Alpha 4/ITGA4抗体
英文名称:
Anti-Integrin Alpha 4/ITGA4 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Integrin Alpha 4/ITGA4 Antibody |
指标别名 | CD49D;IA4;Integrin alpha 4;Integrin alpha IV;ITGA4;VLA 4 subunit alpha |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB |
基因名称 | ITGA4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Integrin alpha 4 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human Integrin alpha 4.The immunogen is located within the last 50 amino acids of Integrin alpha 4. |
计算分子量 | 115kDa |
成分 | Integrin alpha 4 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Integrin alpha 4 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins.Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains.Alpha4 chain associates with either beta1 or beta7 chain.It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain.These ligands included Madcam,VCAM,and fibronectin.Madcam is known as the principal ligand for integrin alpha4beta7.Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7,the gut mucosal homing receptor for peripheral T cells. |
Uniprot ID | P13612 |
基因名全称 | Integrin,alpha 4 (antigen CD49D,alpha 4 subunit of VLA-4 receptor) |
蛋白名全称 | Integrin,alpha 4 (antigen CD49D,alpha 4 subunit of VLA-4 receptor) |
推荐稀释比 | Integrin alpha 4 antibody can be used for the detection of Integrin alpha 4 by Western blot at 1μg/mL.Despite its predicted molecular weight,Integrin alpha4 will often run at higher molecular weight in SDS-PAGE.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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